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Insights into the mechanisms of RNAi

RNA interference (RNAi) is a phenomenon of gene silencing at the mRNA level offering a quick and easy way to determine the function of a gene both in vivo and in vitro. Onufriev's group is a part of multi-disciplinary, multi-institutional team who is trying to develop quantitative models of the process. Our group is looking into the problem at the level of atomic-resolution structures.